DNase I
DNase I

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20μL
HBP000910-1
1mL
HBP000910-3
10mL
HBP000910-4
100μL
HBP000910-5

Cat. No: HBP000910 

Transportation and Storage: Storage Stability: -25℃~-15℃ for storage; Transport Stability: Transport under ice packs; Supplied in: 10 mM Tris-HCl, 2 mM CaCl2, 50% glycerol, pH 7.6 @25℃.

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Product Description

DNase I (Deoxyribonuclease I) is an endodeoxyribonuclease that can digest single- or double- stranded DNA. It recognizes and cleaves phosphodiester bonds to produce monodeoxynucleotides or single- or double- stranded oligodeoxynucleotides with phosphate groups at the 5'-terminal and hydroxyl at the 3'-terminal. The activity of DNase I depends on Ca 2+ and can be activated by divalent metal ions such as Mn 2+ and Zn 2+ . 5 mM Ca 2+ protects the enzyme from hydrolysis. In the presence of Mg 2+ , the enzyme could randomly recognize and cleave any site on any strand of DNA. In the presence of Mn 2+ , the double strands of DNA can be simultaneously recognized and cleaved at almost the same site to form flat end DNA fragments or sticky end DNA fragments with 1-2 nucleotides protruding.


Product Information

Product Name Cat. No Size
DNase I HBP000910-1 20 μL/0.1 KU
HBP000910-3 1 mL/5 KU
HBP000910-4 10 mL/50 KU
HBP000910-5 100 μL/0.5 KU


Transportation and Storage

Storage Stability: -25℃~-15℃ for storage; Transport Stability: Transport under ice packs; Supplied in: 10 mM Tris-HCl, 2 mM CaCl2, 50% glycerol, pH 7.6 @25℃.


Unit Definition 

One unit is defined as the amount of enzyme which will completely degrade 1 µg of pBR322 DNA in 10 minutes at 37°C.

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Service Hotline: +86 400-808-5320

Large-scale production base: Building 6, Precision Medical Industry Base, Wuhan, China

Logistics & Supply Chain Center:417 Main St, Little Rock, AR 72201. United States.

Global Marketing Center: Hzymes Building, Fengxian District, Shanghai, China.

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Contact Us

Service Hotline: +86 400-808-5320

Large-scale production base: Building 6, Precision Medical Industry Base, Wuhan, China.

Logistics & Supply Chain Center:417 Main St, Little Rock, AR 72201. United States.

Global Marketing Center: Hzymes Building, Fengxian District, Shanghai, China.

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