Service Introduction

As a global supplier of core raw materials for the mRNA biotechnology industry, Hzymes Biotech provides comprehensive mRNA Contract Research Organization (CRO) services. Relying on technical platforms such as enzyme gene mining, high-throughput screening, and quantitative analysis and characterization, we have developed raw materials related to the production of biopharmaceuticals and vaccines, as well as "one-stop" solutions. The company has established a high-standard pharmaceutical-grade special enzyme production system, providing products and services to more than 100 biopharmaceutical and vaccine preparation enterprises. Our products are exported to 25 countries and regions. Our mRNA CRO services cover the entire process from sequence design to plasmid preparation, mRNA synthesis, mRNA quality inspection, as well as Lipid Nanoparticle (LNP) encapsulation/quality inspection. We are committed to accelerating the research and development and production of mRNA drugs, and making contributions to human life sciences.

Service Highlights

One-stop Solution:

Hzymes Biotech can provide one-stop proof-of-concept services for mRNA vaccine and drug development, customized synthesis of mRNA and Lipid Nanoparticles (LNPs), mRNA quality inspection services, and mRNA-related process development services, meeting the needs of customers at different stages and levels.

Strict Quality Control System:
Hzymes Biotech has established a strict quality control system and developed a series of quality control-related kits verified by rigorous methodologies. Among them, the detection methods for three important quality control items, namely double-stranded RNA (dsRNA) quantitative detection, DNase residue detection, and RNase residue detection, have been applied by many enterprises in their research, development, and production processes. These methods have also been officially released as a group standard in the "Guidelines for the Development of (Cellular) Immunotherapy Products Based on mRNA-LNP Technology" (T/FDSA 0055-2024).

Innovative mRNA Technology and Application Platform:
Relying on professional knowledge and practical experience, the mRNA technology and application platform independently developed by Hzymes Biotech provides customers with full-process services from sequence design to in vivo biological evaluation through technologies such as efficient plasmid template preparation technology, high-throughput screening technology for the enzymatic catalytic system, and the independently patented real-time fluorescence detection method for quantitative analysis of in vitro transcription (STAR). This accelerates the research and development process of mRNA vaccines and drugs.

• mRNA Vaccine and Drug Proof-of-Concept Services

• Customized synthesis of mRNA and Lipid Nanoparticles (LNPs)
• mRNA quality inspection services

• mRNA-related process development services

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