About Us - Catalyzing life Smart Manufacturing for the Future-Hzymes Biotechnology

Hzymes Biotechnology Co., Ltd. was established in 2015. We are a high-tech enterprise specializing in the research and development, production, application and technical services of core raw materials for bio pharmaceuticals and in vitro diagnostics. Hzymes has two R&D centers in Shanghai and Wuhan, 3 plants located at Shanghai, Wuhan and Yichang, with ISO90001, ISO13485 and GMP grade.

With 20 years of technology accumulation, Hzymes is the only enterprise in China has 5 major IVD & Biopharma enzyme creation technology platforms, including Enzyme gene resource discovery platform, Enzyme directed evolution platform, Enzyme AI Design Platform, Enzyme Catalysis Technology Platform, Enzyme large-scale manufacturing technology platform. Based on the above five technical platforms, Hzymes has being researched and produced hundreds of raw materials for Bio-pharmaceuticals and in vitro diagnostic.
Hzymes has built a pharmaceutical-grade special enzyme production system with super-large production scale and super-high equipment standards. We have provided products and services to more than 2,400 biopharmaceutical, vaccine preparation, and in vitro diagnostic reagent manufacturers at home and abroad. At the same time, our products are exported to more than 40 countries. Relying on academic institutions such as Shanghai Jiaotong University, Shanghai Institute of Experimental Medicine, and Suzhou Institute of Biomedical Engineering of the Chinese Academy of Sciences, Hzymes widely integrates advanced life science technologies to achieve commercial application transformation.
Hzymes takes "Innovative underlying technology Benefiting life" as its corporate mission, practices the corporate values of "customer first, innovation, excellence, responsibility, and win-win", and We will continuously expand our product portfolio and diversify our offerings, striving relentlessly to realize Hzymes' vision of becoming the Global Core Technology Leader in the Biotech Industry!

R&D capabilities
Production scale
Industry impact

22⁺

Years of R&D experiences

50%⁺

Master/PhD talents

116

Global patents count

400⁺

Self-developed products
40000⁺

R&D/Production area (m²)

60000⁺

Fermentation scale (L)

1000

Enzyme output (kg/year)

$15M

Production investment
2400⁺

Global client partners

40⁺

Countries served

100⁺

Awards & Certifications

10⁺

Industry leadership roles

Histories

Key Milestones

Dreams Ignited

Dreams Ignited（2015-2018）

2015

Officially established in Wuhan, China
Recognized under Wuhan's “3551 Optics Valley Talent Program”

2016

Entered the Biochemical Diagnostics Field
Awarded for the “Most Investable Startup” at the 2016 Global Entrepreneurship Week

2017

Launched the first batch of products
Debuted at CACLP Conference in Qingdao, China
Achieved ISO 9001 Quality Management System Certification

2018

Completed Series A funding of ￥60 million
Expanded into the Chemiluminescence Field
Established the first production base in Wuhan, China
Recognized as a National High-tech Enterprise
Awarded for the “Optics Valley Gazelle” in Wuhan East Lake High-tech Zone, China
Accelerated Growth

Accelerated Growth（2019-2021）

2019

Co-founded Glycogene, Inc
Built the enzyme-catalyzed chemical synthesis platform
Entered the molecular diagnostics field
Once again awarded for the "Optics Valley Gazelle Enterprise"
Received the "3551 Most Investment-Worthy Enterprise Award“

2020

Completed Series B/B+ financing, raising over 100 million RMB in total
Established a large-scale manufacturing base in Yichang, China
Entered the mRNA drug raw materials sector
Selected as Vice President Unit of CAIVD (China Association of In Vitro Diagnostics)
Awarded for “2020 China Unicorn Enterprise”
Established the Key Materials Research Institute at the Shanghai Institute of Laboratory Medicine

2021

Completed Series C financing, raising 800 million RMB
Recognized as a Hubei Provincial Enterprise Technology Center
Once again awarded the title of "Optics Valley Gazelle Enterprise"
Won First Prize at the "Maker in China" Wuhan City Competition
Named an Outstanding Enterprise in the China Innovation and Entrepreneurship Competition
Climbing Higher

Climbing Higher（2022-2024）

2022

Established a R&D center in Shanghai, China
Awarded the national-level title of "Specialized, Refined, Characteristic, and Innovative Little Giant"
Received First Prize of the Shanghai Technology Invention Award
Honored as a "Golden Seed" enterprise in a provincial pre-IPO program, Hubei, China
Listed on the 2022 Hurun Global Gazelle Companies List

2023

Entered the synthetic biology field
Selected for Hubei Province's "Chutian Talent Program" for Scientific Innovation Teams
Appointed as Vice President Unit of the China Association for the Promotion of Medical Device Innovation
Appointed as a Council Member of the IVD Branch of the China Association for Medical Devices Industry (CAMDI)

2024

Recognized as a "Golden Seed" enterprise for provincial 2024–2025 pre-IPO program in Hubei, China
Selected for the "Three Gorges Talent Program" as an Industrial Leading Talent Project in Yichang, China
Led the drafting of three group standards for mRNA drug quality control
Appointed as a Council Member of the Shanghai Synthetic Biology Industry Association
Selected as a Key High-Growth Gazelle Enterprise under Wuhan City's 2024 Plan
Awarded the title of "New Species" Potential Unicorn by Hubei Science and Innovation
Listed among the "Top 100 Life Science Service Brands in China 2024"

Looking Ahead

Certification & Honor

Honors

First Prize in Wuhan Maker Competition 2021
Gazelle Enterprises in 2021
3351 Most Investment Value Award
CAIVD Vice President Unit
ISO9001 Certificate
Shanghai Science and Technology Award Certificate
Innovation Award for Upstream Raw Materials of "Chuangzhi Star Cup" - PRK
Innovation Award for Upstream Raw Materials of "Chuangzhi Star Cup" - PRK
Gazelle Enterprises
National Finalist Award of the 10th Innovation and Entrepreneurship Competition
National Outstanding Enterprise Award at the 10th Innovation and Entrepreneurship Competition
High-tech enterprise certificate
Director of the Key Raw Materials Research Institute
Certificate of Market Share of Proteinase K of Hzymes Biotech
Intellectual Property Management System Certificates
Excellent Award of the National Disruptive Technological Innovation Competition
Customs Registration Certificate
Business License
ISO14001 Environmental management system certificate
Science and Technology Giant
Ten in Shanghai "Maker in China" Biomedicine
Eagle High-tech Enterprise of Wuhan
Deputy Chairman of the Raw Materials Committee
Intellectual Property Management System Certification
ISO13485 Management System Certificate
ISO45001-2018 (Occupational Health and Safety Management System Certification)

Learn more

Honors document our legacy and validate our efforts, forged through organization-wide commitment.

These achievements represent the tangible outcomes of our hard work - infused with our sacrifices, yet propelling us toward even brighter horizons.

First Prize in Wuhan Maker Competition 2021
Gazelle Enterprises in 2021
3351 Most Investment Value Award
CAIVD Vice President Unit
ISO9001 Certificate
Shanghai Science and Technology Award Certificate
Innovation Award for Upstream Raw Materials of "Chuangzhi Star Cup" - PRK
Innovation Award for Upstream Raw Materials of "Chuangzhi Star Cup" - PRK
Gazelle Enterprises
National Finalist Award of the 10th Innovation and Entrepreneurship Competition
National Outstanding Enterprise Award at the 10th Innovation and Entrepreneurship Competition
High-tech enterprise certificate
Director of the Key Raw Materials Research Institute
Certificate of Market Share of Proteinase K of Hzymes Biotech
Intellectual Property Management System Certificates
Excellent Award of the National Disruptive Technological Innovation Competition
Customs Registration Certificate
Business License
ISO14001 Environmental management system certificate
Science and Technology Giant
Ten in Shanghai "Maker in China" Biomedicine
Eagle High-tech Enterprise of Wuhan
Deputy Chairman of the Raw Materials Committee
Intellectual Property Management System Certification
ISO13485 Management System Certificate
ISO45001-2018 (Occupational Health and Safety Management System Certification)

State Intellectual Property Administration
A thermophilic esterase AFEST mutant and its screening method and application
Cecosporin C acylase mutant with improved thermal stability and construction method
A novel fructose peptide oxidase and its application
Patent registration book
Compositions for eliminating interference of calcium hydroxybenzenesulfonate drugs on creatinine enzyme detection
A creatinine detection reagent that is anti-interference with calcium hydroxybenzenesulfonate and other drugs
A heat-resistant mutant of proteinase K
A glycerol phosphate oxidase mutant and its screening method, preparation method and application
Method for preparing culture medium and alkaline phosphatase for fermentation
Cysthione-β-lyase and its preparation method and application
A lyophilized protective agent for sphingomyelinase and preparation method
A latex-enhanced immunoturbidity reagent and a method for improving the detection accuracy of latex-enhanced immunoturbidity reagent
Preparation and application of high salt resistance and high activity DNase I mutants
A method for preparing latex enhanced immune turbiditrophiogenic reagent using recombinant antibodies
Stable recombinant trypsin, preparation method and application
A preparation method for fructosyl peptide oxidase that enhances activity
A proteinase K mutant and its preparation method
A proteinase K mutant with improved thermal stability
Application and method for Genapo1 X-080 to improve cholesterol esterase activity
Hzymes chemical raw materials and product inventory management platform V1.0
Hzymes enzyme preparation production planning management system V1.0
Fermentation tank temperature control real-time management system V1.0
Freeze-dryer intelligent integrated control software V1.0
Hzymes Biotechnology Chemical Reagent Retail System V1.0
A batch protein separation and purification device
An intelligent ultraviolet spectrophotometer
An instrument for rapid protein dyeing and transfer printing
An automatic protein detection and purification device
A high-speed tube centrifuge with online detection of turbidity of centrifugal fluid
A large fermentation sampling device
A fermentation flow material addition device
A sterilization and filtration device
A fast cooling device for bacterial strain fermentation tank
An air filtration device for liquid bacteria fermentation tank
Reagent Kit Appearance Design