Product Overview

FAST LNP (in vivo-System Delivery) is a ready-to-use lipid nanoparticle (LNP) formulation reagent specifically designed for in vivo mRNA delivery and RNA drug development applications. It enables rapid and efficient encapsulation of mRNA through a simple mixing process, allowing researchers to generate functional mRNA-LNP particles within 1 minute without the need for specialized microfluidic equipment.

Compared with traditional LNP preparation methods that typically require complex encapsulation procedures, extended processing time, and downstream purification steps, FAST LNP provides a streamlined one-step workflow with zero dead volume and minimal sample loss. The formulation supports direct encapsulation of microgram-level mRNA inputs, making it especially suitable for animal studies, in vivo expression validation, and rapid screening of RNA therapeutics.

FAST LNP (in vivo-System Delivery) features a proprietary lipid composition optimized for mammalian in vivo delivery. The formulation contains no ethanol components, ensuring a high biosafety profile for preclinical research applications. It eliminates the need for additional purification or buffer exchange, significantly reducing experimental complexity, cost, and turnaround time.

This product is designed for researchers developing mRNA vaccines, RNA therapeutics, gene editing applications, and in vivo RNA delivery platforms.

Key Features

Ready-to-Use mRNA Encapsulation Solution

FAST LNP enables instant LNP formulation through simple mixing of LNP stock solution with mRNA. The entire encapsulation process can be completed within 1 minute, providing a rapid solution for in vivo RNA delivery studies.

Ultra-Low Sample Loss with Zero Dead Volume

The optimized formulation workflow minimizes sample loss during preparation and supports encapsulation using microgram-level mRNA inputs, making it suitable for valuable or limited RNA samples.

No Specialized Equipment Required

Unlike traditional microfluidic-based LNP preparation, FAST LNP does not require dedicated encapsulation instruments, reducing equipment investment, operational complexity, and laboratory workload.

Proprietary Lipid Composition

FAST LNP utilizes an exclusive lipid formulation designed for efficient mRNA delivery. The formulation has no patent conflict with Moderna or BioNTech/Pfizer LNP systems.

One-Step Workflow for Rapid In Vivo Validation

Direct formulation and immediate application enable accelerated animal experiments, shortening the cycle from mRNA design to in vivo expression evaluation.

High Biosafety Profile

The formulation contains no ethanol components, supporting safer handling and reducing concerns associated with residual organic solvents.

Applications

• In Vivo mRNA Delivery Studies

• mRNA Vaccine Development

• RNA Therapeutic Development

• High-Throughput Screening of mRNA Candidates

• Gene Editing Efficiency Evaluation

• Animal Immunization and Antibody Production Studies

• Rapid In Vivo Expression Validation

• LNP Encapsulation of Trace RNA Samples

Performance Data

Systemic mRNA Delivery Performance of FAST LNP

In Vivo Systemic Expression Evaluation of FAST LNP Formulations

In vivo evaluation of FAST LNP formulations demonstrating systemic mRNA delivery and protein expression performance across mouse models.

Multi-Organ mRNA Delivery Profile of FAST LNP

Evaluation of FAST LNP biodistribution and mRNA delivery across multiple organs, demonstrating broad systemic delivery capability.

FAST LNP In Vivo Distribution and Expression Evaluation

Organ-Specific Biodistribution Analysis of FAST LNP

In vivo biodistribution analysis of FAST LNP showing mRNA delivery patterns and expression profiles across different tissues.

Systemic Protein Expression Evaluation After FAST LNP Administration

Evaluation of systemic FAST LNP delivery performance demonstrating efficient mRNA translation and protein expression following administration.

Longitudinal In Vivo Expression Analysis of FAST LNP

Long-term evaluation of FAST LNP-mediated mRNA delivery showing sustained protein expression following systemic administration.

FAQ

Q1: What is FAST LNP used for?

FAST LNP is a ready-to-use LNP formulation reagent designed for rapid mRNA encapsulation and in vivo RNA delivery studies, including mRNA vaccines, RNA therapeutics, and gene editing research.

Q2: How long does the FAST LNP encapsulation process take?

The complete mRNA encapsulation process can be completed within approximately 1 minute through a simple mixing procedure.

Q3: Does FAST LNP require specialized encapsulation equipment?

No. FAST LNP does not require microfluidic instruments or other specialized encapsulation equipment, making it suitable for rapid laboratory-scale RNA delivery studies.

Q4: What is the minimum mRNA input required?

FAST LNP supports encapsulation with microgram-level mRNA input, enabling efficient delivery even when RNA samples are limited.

Q5: How should FAST LNP be transported and stored?

FAST LNP should be transported under -45°C to 25°C and stored at -85°C to -65°C before use.

Q6: How long can formulated FAST LNP-mRNA particles be stored?

After encapsulation, FAST LNP-mRNA particles can be stored at 2–8°C for up to 35 days.