Service introduction

The ELISA method can detect the total content of residual host protein in the test sample, but the detection efficiency of this method is affected by the coverage rate of the residual HCP by the antibody used, and by the difference between the standard and the test sample. Therefore, according to the product production process, the host protein standard and specific antiserum are prepared according to the process, and the establishment of the corresponding detection method can more truly reflect the residual host protein of the test sample.
Hzymes has a professional product R&D team and technical service team. With the company's rich protein and antibody product pipeline, it has rich experience in the research and development of HCP-specific antibodies. We can design scientific experimental schemes according to different needs, develop efficient detection methods, and conduct comprehensive and accurate methodological verification to provide customized development services for host HCP for biopharmaceutical R&D customers.

Service scope

• HCP detection kit coverage verification
• Development of customized HCP kits for CHO, E. coli, Yeast and other biopharmaceutical expression hosts

Service highlights

• With rich experience in HCP kit testing and a deep understanding of the process route, we can help customers design reasonable antigen preparation strategies.
• GMP-compliant analytical service laboratories can directly perform method validation and transfer to customer factories.
• With independent intellectual property rights and polyclonal antibody foundation, high-abundance antigens are removed, and the customer's first immunization is the second immunization, which can reduce costs and increase efficiency.
• There are successful cases of kit development, and cooperation accelerates development.

• Perfect production system, one-stop delivery.

Case sharing

Antibody customization example

Project process