Product Description
Ribonuclease R (RNase R) from E. coli, is a magnesium-dependent 3’→5’ exoribonuclease that digests essentially all linear RNAs but does not digest lariat, circular RNA structures or double-stranded RNA with 3' overhangs less than 7 nucleotides. RNase R is commonly used in gene expression and alternative splicing studies to digest linear RNA for the enrichment of circular RNA (circRNAs) or lariat RNA. RNase R digests linear RNAs to enrich for circular RNAs used for intronic cDNA library construction from total RNA.
Product Information
| Product Name | Cat. No. | Size |
| RNase R (20U/μL) | HBP004600-1 | 25μL |
| HBP004600-2 | 250μL |
Transportation and storage
Transportation under 0°C and storage at -25～ -18°C.
Activity unit definition
One unit converts 1 μg of poly-r(A) into acid-soluble nucleotides in 10 minutes at 37 °C
