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Home · Products · Products · Molecular Diagnostics · Nucleic Acid Pre-processing · DNase I · DNase I (Lyophilized Powder) ·
DNase I (Lyophilized Powder)
DNase I (Lyophilized Powder)

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2. 5 KU
HMD4007A-02

Cat. No: HMD4007A

Transportation and Storage:
Storage Stability: -25~ -15℃ for storage.
Transport Stability: Transport under ice packs.

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Product Description


DNase I (Deoxyribonuclease I) is an endodeoxyribonuclease that can digest single- or double- stranded DNA. It recognizes and cleaves phosphodiester bonds to produce oligodeoxynucleotide or single or double- stranded oligodeoxynucleotides with phosphate groups at the 5'-terminal and hydroxyl at the 3'-terminal. The activity of DNase I depends on Ca2+ and can be activated by divalent metal ions such as Mn2+ and Zn2+ . 5 mM Ca2+ protects the enzyme from hydrolysis. In the presence of Mg2+ , the enzyme could randomly recognize and cleave any site on any strand of DNA. In the presence of Mn2+ , the double strands of DNA can be simultaneously recognized and cleaved at almost the same site to form flat end DNA fragments or sticky end DNA fragments with 1-2 nucleotides protruding.



Product Information


Product Name Cat. No Size
DNase I, RNase-free ( Lyophilized powder ) HMD4007A-02 2. 5 KU



Transportation and Storage


Storage Stability: -25~ -15℃ for storage.
Transport Stability: Transport under ice packs.

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