Product Overview

2-Chloro-4-nitrophenyl-α-L-fucopyranoside (CNP-AFU, CAS: 157843-41-9) is a highly specific substrate for α-L-fucosidase (AFU), a critical biochemical raw material for the auxiliary diagnosis of clinical hepatobiliary diseases and primary liver cancer.

Synthesized via proprietary in-house technology, this product offers ≥99% purity, excellent thermal stability, and consistent batch-to-batch quality. Compatible with fully automated clinical chemistry analyzers, it is widely used for quantitative AFU activity assays, enzymatic research, and large-scale production of in vitro diagnostic reagent.

Key Features

High Purity & Excellent Thermal Stability

Proprietary synthesis technology ensures ≥99% purity and excellent thermal stability, reducing background interference and improving result accuracy.

Large-Scale Production Capacity

Large single-batch production scale with controlled batch consistency, ensuring stable supply for large-scale reagent manufacturing.

Dual Inspection (Physicochemical & Biochemical)

Besides routine physicochemical tests, additional biochemical applicability evaluation is conducted to meet dual quality specifications.

Responsive Technical Support

In-house R&D team provides timely, professional technical support and customized services.

Applications

Clinical Diagnostic Reagents

Core substrate for α-L-fucosidase (AFU) activity assays, used for quantitative detection of AFU in serum/plasma to support early screening and diagnosis of primary liver cancer, cirrhosis, and other hepatobiliary diseases, compatible with various fully automated clinical chemistry analyzers.

Enzymatic & Medical Research

Used for α-L-fucosidase activity determination, kinetic analysis, inhibitor screening, and research on related metabolic pathways and disease mechanisms.

Diagnostic Reagent Manufacturing

Provides high-purity, batch-stable raw materials for in vitro diagnostic reagent manufacturers, supporting large-scale production and quality control of AFU assay kits.

Specification

Item	Specification
Product Name	2-Chloro-4-nitrophenyl-α-L-fucopyranoside (CNP-AFU)
Catalog No.
CAS No.	157843-41-9
Molecular Formula	C₁₂H₁₄ClNO₇
Molecular Weight	319.70
Purity	≥99%（HPLC）
Appearance	White powder
λmax	405 nm（Colorimetric wavelength）
Storage	Short-term storage: 2-8°C, sealed, dry, and protected from light. For long-term storage, it is recommended to store at -25 to -15°C, also protected from light.
Product Line	Clinical chemistry enzyme substrates

Performance Data

Purity Verification

HPLC chromatogram presents a single principal peak with no obvious impurity peaks; purity ≥99%, effectively lowering background noise during detection.

A Brand

HZYMES