NGS Protease K is a serine protease with high enzyme activity and wide substrate specificity. The enzyme preferentially decomposes ester bonds and peptide bonds adjacent to the C-terminal of hydrophobic amino acids, sulfur-containing amino acids and aromatic amino acids. So, it is often used to degrade proteins into short peptides. NGS Protease K is a typical serine protease with the Asp39-His69-Ser224 catalytic triad which is unique to serine proteases, and the catalytic center is surrounded by tow Ca2+ binding sites for stabilization, maintaining high enzyme activity under a wider range of conditions.
Product Information
| Product Name | Cat. No | Size |
| Proteinase K (lyophilized powder for NGS) |
HH4507-01 | 100 mg |
| HH4507-02 | 1 g | |
| HH4507-03 | 10 g | |
| HH4507-04 | 100 g |
One unit (U) is defined as the amount of enzyme required to hydrolyze casein to produce 1 μmol tyrosine per minute under the following conditions.
