Introduction

As mRNA-based therapeutics continue to reshape the biomedical landscape, the need for reliable, ready-to-use mRNA raw materials is more pressing than ever. At Hzymes Biotech, we specialize in delivering high-performance mRNA products optimized for in vitro transcription, cell transfection, animal studies, and therapeutic development workflows.

Whether you are screening LNP formulations, conducting protein expression studies, or developing next-generation mRNA vaccines and gene therapies, Hzymes provides a complete suite of ready-to-use mRNA solutions and custom mRNA synthesis services.

Features

1.      Good stability: 2-8°C can be stored for a month, and can be repeatedly freeze and thaw for more than 10 times.

2.      Excellent performance: the integrity can reach 90%, the cap rate of more than 97%.

3.      The product was verified by cell expression: the protein expression level was higher than the competing products

4.      Complete categories, stable supply: spot supply, short period of delivery

In the study of mRNA drugs, mRNA solution is often used as cell experiment, animal experiment control, purification process exploration, filler screening and other stages Hyzmes provides a variety of mRNA solutions, and accepts customized mRNA synthesis service.

Hzymes mRNA Product Portfolio

EGFP mRNA

1.      Integrity >90%

2.      Capping rate >90%

3.      High protein expression in cells.

The protein expression of EGFP mRNA is high and can last for at least 72 hours.

Fluc mRNA

1.        Good stability: Can be stored at 2-8°C for one month and can be frozen and thawed more than 10 times.

2.        Excellent performance: Integrity can reach 90%, and cap rate is above 98%.

3.        Product verified by cell expression: Protein expression is higher than that of competing products.

4.        Complete product range and stable supply: Available in stock with short delivery times.

The protein expression of Fluc mRNA is high in different cells

Fluc mRNA-LNP was intramuscularly injected into a mouse (6-8week, female) and live imaging. The protein expression of Fluc mRNA is high in vivo.

Cas9 mRNA

1.      Integrity >90%

2.      Capping rate >90%

3.      High protein expression in vitro.

Cas9 protein was successfully expressed with cas9 mRNA (N1-UTP) in 293T cells.

COVID-19 RBD (1000nt) mRNA

1.      Integrity >85%

2.      Capping rate >90%

3.      High protein expression in vitro.

RBD protein can be successfully expressed by RBD mRNA in 293T cells.

COVID-19 Spike (4000 nt) mRNA

1.      Integrity>85%

2.      Capping rate >90%

3.      High protein expression in vitro.

Spike protein can be successfully expressed by Spike mRNA in 293T cells.

Human EPO mRNA

1.      Integrity>90%

2.      Capping rate >90%

3.      High protein expression in vitro.

It is proved that the hEPO protein can be successfully expressed in hEPO mRNA in293T cells. The hEPO protein secretion was competent, and the expression was much higher in the supernatant than intracellular.

Mouse EPO mRNA

1.      Integrity >90%

2.      Capping rate >90%

3.      High protein expression in vitro.

It was demonstrated that the mEPO protein can be successfully expressed by mEPO mRNA in 293T cells. The mEPO protein was secreted highly, with much higher expression in the supernatant than intracellular.

EGFP saRNA

1.      Integrity >90%

2.      Long expression period: >26 days

3.      High protein expression in vitro.

It has been shown that EGFP saRNA can be expressed for up to 26 days, longer and in lower doses compared with linear EGFP MRNA.

circRNA eGFP

5.        Good stability: Can be stored at 2-8°C for one month and can be frozen and thawed more than 10 times.

6.        Excellent performance: Integrity can reach 90%, and cap rate is above 98%.

7.        Product verified by cell expression: Protein expression is higher than that of competing products.

8.        Complete product range and stable supply: Available in stock with short delivery times.

circRNA Fluc

Applications Across mRNA Drug Development

Our mRNA products are suitable for:

• In vitro transcription & protein expression screening
• mRNA-LNP formulation optimization
• Immunogenicity & efficacy studies
• Cell line engineering and reporter assays
• Preclinical proof-of-concept studies

Why Hzymes?

With decades of experience in nucleic acid technologies, Hzymes stands as your trusted mRNA manufacturing partner. We combine high-quality synthesis, rigorous QC, and fast response times to accelerate your mRNA R&D programs.