PCR Lyophilized Reagents: Ushering in a New Era of Convenient Testing!

Polymerase Chain Reaction (PCR) technology, a revolutionary advancement in molecular biology, is widely applied in disease diagnosis, genetic testing, forensic identification, and many other fields.

Traditional PCR systems require storage in low-temperature environments, making them vulnerable to temperature fluctuations and contamination.

This results in high transportation costs and inconvenience during use, limiting their applications in resource-limited areas and on-site rapid testing. Consequently, the development of user-friendly, stable, and easily transportable PCR reagents has become a critical research focus for the industrialization of molecular diagnostics. The advent of lyophilized PCR reagents has effectively addressed these challenges.

What are Lyophilized PCR Reagents?

Lyophilized PCR reagents involve freeze-drying all components necessary for PCR reactions (including DNA polymerase, reverse transcriptase, dNTPs, MgCl₂, buffers, and primers) into stable powder or lyophilized bead forms. Simply adding water to rehydrate them allows for immediate PCR reaction setup. Compared to traditional liquid PCR reagents, lyophilized versions offer greater stability, portability, and ease of use while being compatible with automated equipment. These advantages significantly broaden the real-world application of PCR technology in fields such as pathogen rapid diagnostics, genetic testing, and forensic analysis.

Expanding Applications and Global Significance

As PCR technology continues to evolve, the scope of lyophilized PCR reagents will further expand. In resource-limited regions, particularly in developing countries and international markets, their stability during transportation and cost advantages will play an increasingly important role. This makes them invaluable for disease prevention and the public health sector.

Featured Product

Convenient, Multiplex, Sensitive, and Stable MS qPCR/RT-qPCR Lyophilizable Premix

Product Overview:

This product supports the addition of primers and probes before lyophilization, allowing for direct sample nucleic acid addition during subsequent use. It is compatible with singleplex or multiplex detection and uses a UDG-dUTP anti-contamination system to effectively prevent aerosol contamination of amplification products.

Product Advantages

1.Lyophilization-Ready: Easy to prepare, store, and transport.

2.Anti-Contamination: Integrated UDG-dUTP system reduces contamination risks.

3.High Sensitivity and Stability: Enhanced performance under challenging conditions.

4.Adaptability: Compatible with automated systems and multiplex detection setups.

Success Stories

1. Respiratory Testing:

• HzymesHMD3915 shows excellent linearity in amplifying samples with 200 copies/mL, with high Rn values and consistent Ct values.

2. Thermal Stability:

HMD3915 lyophilized beads with influenza A primer-probe remain stable after accelerated aging at 50°C for 28 days.

3. HPV Testing:

• HMD3811 demonstrates superior signal values and sensitivity compared to control groups.

4.Animal Target Testing:

• HMD3915 outperforms control groups in fluorescence intensity and sensitivity.

Order:

In the future, Hzymes biotech will always remember its original intention and persist in meticulous cultivation in the IVD field. It will adhere to independent research and development, accelerate the construction of a world-class specialty enzyme production platform, and achieve import substitution of core enzyme raw materials in the field of biomedicine in China. It will collaborate with leading biopharmaceutical companies to expand their global presence and contribute to the advancement of the industry.